Jan 25 2009
Diseases treatable with cord blood
Below is a list of diseases for which autologous or allogeneic hematopoietic cell transplant may be a treatment. The list includes diagnoses for which transplant is a standard treatment as well as diagnoses for which the role of transplant is a somewhat newer option. The current distribution of transplants performed by diagnosis follows.
Leukemias and lymphomas, including:
• Acute myelogenous leukemia
• Acute lymphoblastic leukemia
• Chronic myelogenous leukemia
• Chronic lymphocytic leukemia
• Juvenile myelomonocytic leukemia
• Hodgkin’s lymphoma
• Non-Hodgkin’s lymphoma
Multiple myeloma and other plasma cell disordersLeukemias and lymphomas, including:
• Acute myelogenous leukemia
• Acute lymphoblastic leukemia
• Chronic myelogenous leukemia
• Chronic lymphocytic leukemia
• Juvenile myelomonocytic leukemia
• Hodgkin’s lymphoma
• Non-Hodgkin’s lymphoma
Multiple myeloma and other plasma cell disorders
Severe aplastic anemia and other marrow failure states, including:
• Severe aplastic anemia
• Fanconi anemia
• Paroxysmal nocturnal hemoglobinuria (PNH)
• Pure red cell aplasia
• Amegakaryocytosis / congenital thrombocytopenia
SCID and other inherited immune system disorders, including:
• Severe combined immunodeficiency (SCID, all sub-types)
• Wiskott-Aldrich syndrome
Hemoglobinopathies, including:
• Beta thalassemia major
• Sickle cell disease
Hurler’s syndrome and other inherited metabolic disorders, including:
• Hurler’s syndrome (MPS-IH)
• Adrenoleukodystrophy
• Metachromatic leukodystrophy
Myelodysplastic and myeloproliferative disorders, including:
• Refractory anemia (all types)
• Chronic myelomonocytic leukemia
• Agnogenic myeloid metaplasia (myelofibrosis)
Familial erythrophagocytic lymphohistiocytosis and other histiocytic disorders
Other malignancies
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